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Igf2/H19 Imprinting Control Region (ICR): An Insulator or a Position-Dependent Silencer?
The imprinting control region (ICR) located far upstream of the H19 gene, in conjunction with enhancers, modulates the transcription of Igf2 and H19 genes in an allele-specific manner. On paternal inheritance, the methylated ICR silences the H19 gene and indirectly facilitates transcription from the...
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| Publicado no: | ScientificWorldJournal |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
TheScientificWorldJOURNAL
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6084035/ https://ncbi.nlm.nih.gov/pubmed/12806090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2001.50 |
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