RACK1 and CIS Mediate the Degradation of BimEL in Cancer Cells

RACK1 is a 7-WD motif-containing protein with numerous downstream effectors regulating various cellular functions. Using a yeast two-hybrid screen, we identified dynein light chain 1 as a novel interacting partner of RACK1. Additionally, we demonstrated that RACK1 formed a complex with DLC1 and Bim,...

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Detalhes bibliográficos
Main Authors: Zhang, Weizhou, Cheng, George Zhi, Gong, Jianli, Hermanto, Ulrich, Zong, Cong Susan, Chan, Joseph, Cheng, Jin Quan, Wang, Lu-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423247/
https://ncbi.nlm.nih.gov/pubmed/18420585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802360200
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