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Decreased Ceramide Transport Protein (CERT) Function Alters Sphingomyelin Production following UVB Irradiation
Increased cellular ceramide accounts in part for UVB irradiation-induced apoptosis in cultured human keratinocytes with concurrent increased glucosylceramide but not sphingomyelin generation in these cells. Given that conversion of ceramide to non-apoptotic metabolites such as sphingomyelin and gluc...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423244/ https://ncbi.nlm.nih.gov/pubmed/18411267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800799200 |
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