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Casein Kinase Iγ2 Down-Regulates Trafficking of Ceramide in the Synthesis of Sphingomyelin

Intracellullar trafficking of lipids is fundamental to membrane biogenesis. For the synthesis of sphingomyelin, ceramide is transported from the endoplasmic reticulum to the Golgi apparatus by the ceramide transfer protein CERT. CERT is phosphorylated by protein kinase D at S132 and subsequently mul...

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Main Authors: Tomishige, Nario, Kumagai, Keigo, Kusuda, Jun, Nishijima, Masahiro, Hanada, Kentaro
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613112/
https://ncbi.nlm.nih.gov/pubmed/19005213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0669
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