Nasal Vaccination with the 40-Kilodalton Outer Membrane Protein of Porphyromonas gingivalis and a Nontoxic Chimeric Enterotoxin Adjuvant Induces Long-Term Protective Immunity with Reduced Levels of Immunoglobulin E Antibodies

In this study, we demonstrated that the 40-kDa outer membrane protein of Porphyromonas gingivalis (40-kDa OMP) nasally administered with a nontoxic chimeric adjuvant that combines the A subunit of mutant cholera toxin E112K with the pentameric B subunit of heat-labile enterotoxin from enterotoxigeni...

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Detaylı Bibliyografya
Asıl Yazarlar: Momoi, Fumiki, Hashizume, Tomomi, Kurita-Ochiai, Tomoko, Yuki, Yoshikazu, Kiyono, Hiroshi, Yamamoto, Masafumi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423079/
https://ncbi.nlm.nih.gov/pubmed/18411288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01502-07
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