KSR stimulates Raf-1 activity in a kinase-independent manner
Kinase suppressor of Ras (KSR) is an evolutionarily conserved component of Ras-dependent signaling pathways. Here, we find that murine KSR (mKSR1) translocates from the cytoplasm to the plasma membrane in the presence of activated Ras. At the membrane, mKSR1 modulates Ras signaling by enhancing Raf-...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
|---|---|
| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1997
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24217/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.24.12792 |
| Etiketak: |
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|