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Non-redundant Functions of Cyclooxygenases: Oxygenation of Endocannabinoids

The two cyclooxygenase (COX) enzymes catalyze the oxygenation of arachidonic acid to prostaglandin endoperoxides, which are the common intermediates in the biosynthesis of the bioactive lipids prostaglandins and thromboxane. COX-1 and COX-2 are ∼60% identical in amino acid sequence, exhibit highly h...

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Bibliografski detalji
Glavni autori: Rouzer, Carol A., Marnett, Lawrence J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2417164/
https://ncbi.nlm.nih.gov/pubmed/18250160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800005200
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