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A Morpholino Oligomer Targeting Highly Conserved Internal Ribosome Entry Site Sequence Is Able To Inhibit Multiple Species of Picornavirus

Members of the genera Enterovirus and Rhinovirus (family Picornaviridae) cause a wide range of human diseases. An established vaccine is available only for poliovirus, and no effective therapy is available for the treatment of infections caused by any pathogenic picornavirus. Peptide-conjugated phos...

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Detalhes bibliográficos
Main Authors: Stone, Jeffrey K., Rijnbrand, Rene, Stein, David A., Ma, Yinghong, Yang, Yan, Iversen, Patrick L., Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415775/
https://ncbi.nlm.nih.gov/pubmed/18347107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00011-08
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