Population Pharmacokinetics of Rifampin in Pulmonary Tuberculosis Patients, Including a Semimechanistic Model To Describe Variable Absorption

This article describes the population pharmacokinetics of rifampin in South African pulmonary tuberculosis patients. Three datasets containing 2,913 rifampin plasma concentration-time data points, collected from 261 South African pulmonary tuberculosis patients aged 18 to 72 years and weighing 28.5...

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Main Authors: Wilkins, Justin J., Savic, Radojka M., Karlsson, Mats O., Langdon, Grant, McIlleron, Helen, Pillai, Goonaseelan, Smith, Peter J., Simonsson, Ulrika S. H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Clinical Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415769/
https://ncbi.nlm.nih.gov/pubmed/18391026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00461-07
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