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Biological Activities of Novel Gyrase Inhibitors of the Aminocoumarin Class
Thirty-one aminocoumarin antibiotics derived from mutasynthesis experiments were investigated for their biological activities. Their inhibitory activities toward Escherichia coli DNA gyrase were determined in two different in vitro assays: an ATPase assay and a DNA supercoiling assay. The assays gav...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2415755/ https://ncbi.nlm.nih.gov/pubmed/18347114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01235-07 |
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