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Biological Activities of Novel Gyrase Inhibitors of the Aminocoumarin Class

Thirty-one aminocoumarin antibiotics derived from mutasynthesis experiments were investigated for their biological activities. Their inhibitory activities toward Escherichia coli DNA gyrase were determined in two different in vitro assays: an ATPase assay and a DNA supercoiling assay. The assays gav...

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Hlavní autoři: Anderle, Christine, Stieger, Martin, Burrell, Matthew, Reinelt, Stefan, Maxwell, Anthony, Page, Malcolm, Heide, Lutz
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415755/
https://ncbi.nlm.nih.gov/pubmed/18347114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01235-07
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