QR code

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids

Calcium influx through store-operated calcium release-activated calcium channels (CRAC) is required for T cell activation, cytokine synthesis, and proliferation. The CD95 (Apo-1/Fas) receptor plays a role in self-tolerance and tumor immune escape, and it mediates apoptosis in activated T cells. In t...

Volledige beschrijving

Bewaard in:
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lepple-Wienhues, Albrecht, Belka, Claus, Laun, Tilmann, Jekle, Andreas, Walter, Birgit, Wieland, Ulrich, Welz, Martina, Heil, Luzia, Kun, Jutta, Busch, Gillian, Weller, Michael, Bamberg, Michael, Gulbins, Erich, Lang, Florian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1999
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10570152/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.24.13795
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items