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Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response
RNA recognition receptors are important for detection of and response to viral infections. RIG-I and MDA5 are cytoplasmic DEX(D/H) helicase proteins that can induce signaling in response to RNA ligands, including those from viral infections. LGP2, a homolog of RIG-I and MDA5 without the caspase recr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2414291/ https://ncbi.nlm.nih.gov/pubmed/18411269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800542200 |
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