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Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response

RNA recognition receptors are important for detection of and response to viral infections. RIG-I and MDA5 are cytoplasmic DEX(D/H) helicase proteins that can induce signaling in response to RNA ligands, including those from viral infections. LGP2, a homolog of RIG-I and MDA5 without the caspase recr...

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Main Authors: Murali, Ayaluru, Li, Xiaojun, Ranjith-Kumar, C. T., Bhardwaj, Kanchan, Holzenburg, Andreas, Li, Pingwei, Kao, C. Cheng
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414291/
https://ncbi.nlm.nih.gov/pubmed/18411269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800542200
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