Defective C-propeptides of the Proα2(I) Chain of Type I Procollagen Impede Molecular Assembly and Result in Osteogenesis Imperfecta

Lignende værker

• Mutations That Alter the Carboxy-Terminal-Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta Phenotype
  af: Cundy, Tim, et al.
  Udgivet: (2018)
• Disruption of one intra-chain disulphide bond in the carboxyl-terminal propeptide of the proα1(I) chain of type I procollagen permits slow assembly and secretion of overmodified, but stable procollagen trimers and results in mild osteogenesis imperfecta
  af: Pace, J., et al.
  Udgivet: (2001)
• Reduced secretion of structurally abnormal type I procollagen in a form of osteogenesis imperfecta.
  af: Barsh, G S, et al.
  Udgivet: (1981)
• Type I osteogenesis imperfecta: a nonfunctional allele for pro alpha 1 (I) chains of type I procollagen.
  af: Barsh, G S, et al.
  Udgivet: (1982)
• Substitutions for arginine at position 780 in triple helical domain of the α1(I) chain alter folding of the type I procollagen molecule and cause osteogenesis imperfecta
  af: Makareeva, Elena, et al.
  Udgivet: (2018)