A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo.

The integration of retroviral DNA proceeds through two steps: trimming of the termini to expose new 3' OH ends, and the transfer of those ends to the phosphates of target DNA. We have examined the ability of the Moloney murine leukemia virus integrase protein (IN) to trim the termini of the preinteg...

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Vydáno v:	J Virol
Hlavní autoři:	Murphy, J E, Goff, S P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1629963/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.8.5092-5095.1992
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