Regulatory Mechanisms by Which Barrier-to-Autointegration Factor Blocks Autointegration and Stimulates Intermolecular Integration of Moloney Murine Leukemia Virus Preintegration Complexes

Retroviral integration is mediated by a preintegration complex (PIC) which contains the viral DNA made by reverse transcription together with associated protein factors. Prior to association with target DNA, the PIC must avoid suicidal intramolecular integration of its viral DNA (autointegration). W...

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Detalles Bibliográficos
Main Authors: Suzuki, Youichi, Craigie, Robert
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136854/
https://ncbi.nlm.nih.gov/pubmed/12414981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.12376-12380.2002
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