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Assembly and Catalysis of Concerted Two-End Integration Events by Moloney Murine Leukemia Virus Integrase

Retroviral integration results in the stable and coordinated insertion of the two termini of the linear viral DNA into the host genome. An in vitro concerted two-end integration reaction catalyzed by the Moloney murine leukemia virus (M-MuLV) integrase (IN) was used to investigate the binding and co...

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Detalhes bibliográficos
Main Authors: Yang, Fan, Roth, Monica J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114526/
https://ncbi.nlm.nih.gov/pubmed/11559787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9561-9570.2001
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