Regulatory Mechanisms by Which Barrier-to-Autointegration Factor Blocks Autointegration and Stimulates Intermolecular Integration of Moloney Murine Leukemia Virus Preintegration Complexes

Retroviral integration is mediated by a preintegration complex (PIC) which contains the viral DNA made by reverse transcription together with associated protein factors. Prior to association with target DNA, the PIC must avoid suicidal intramolecular integration of its viral DNA (autointegration). W...

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Bibliografiske detaljer
Main Authors: Suzuki, Youichi, Craigie, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136854/
https://ncbi.nlm.nih.gov/pubmed/12414981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.12376-12380.2002
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