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PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

Parkinson's disease (PD) is a common age-related neurodegenerative disease and it is critical to develop models which recapitulate the pathogenic process including the effect of the ageing process. Although the pathogenesis of sporadic PD is unknown, the identification of the mendelian genetic...

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Detalhes bibliográficos
Main Authors: Wood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey S. Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma, Downward, Julian, Mansfield, Louise, Jat, Parmjit, Taylor, Joanne, Heales, Simon, Duchen, Michael R., Latchman, David, Tabrizi, Sarah J., Wood, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413012/
https://ncbi.nlm.nih.gov/pubmed/18560593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002455
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