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Dopamine Induced Neurodegeneration in a PINK1 Model of Parkinson's Disease

BACKGROUND: Parkinson's disease is a common neurodegenerative disease characterised by progressive loss of dopaminergic neurons, leading to dopamine depletion in the striatum. Mutations in the PINK1 gene cause an autosomal recessive form of Parkinson's disease. Loss of PINK1 function cause...

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Detalhes bibliográficos
Main Authors: Gandhi, Sonia, Vaarmann, Annika, Yao, Zhi, Duchen, Michael R., Wood, Nicholas W., Abramov, Andrey Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360782/
https://ncbi.nlm.nih.gov/pubmed/22662171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037564
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