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Dopamine Induced Neurodegeneration in a PINK1 Model of Parkinson's Disease

BACKGROUND: Parkinson's disease is a common neurodegenerative disease characterised by progressive loss of dopaminergic neurons, leading to dopamine depletion in the striatum. Mutations in the PINK1 gene cause an autosomal recessive form of Parkinson's disease. Loss of PINK1 function cause...

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書誌詳細
主要な著者: Gandhi, Sonia, Vaarmann, Annika, Yao, Zhi, Duchen, Michael R., Wood, Nicholas W., Abramov, Andrey Y.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360782/
https://ncbi.nlm.nih.gov/pubmed/22662171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037564
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