PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

Parkinson's disease (PD) is a common age-related neurodegenerative disease and it is critical to develop models which recapitulate the pathogenic process including the effect of the ageing process. Although the pathogenesis of sporadic PD is unknown, the identification of the mendelian genetic...

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Autores principales: Wood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey S. Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma, Downward, Julian, Mansfield, Louise, Jat, Parmjit, Taylor, Joanne, Heales, Simon, Duchen, Michael R., Latchman, David, Tabrizi, Sarah J., Wood, Nicholas W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413012/
https://ncbi.nlm.nih.gov/pubmed/18560593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002455
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