Synthesis of tenascin and laminin beta2 chain in human bronchial epithelial cells is enhanced by cysteinyl leukotrienes via CysLT(1 )receptor

BACKGROUND: Cysteinyl leukotrienes (CysLTs) are key mediators of asthma, but their role in the genesis of airway remodeling is insufficiently understood. Recent evidence suggests that increased expression of tenascin (Tn) and laminin (Ln) β2 chain is indicative of the remodeling activity in asthma,...

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Bibliographic Details
Main Authors: Altraja, Siiri, Kadai, Martin, Rekker, Erki, Altraja, Alan
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2412865/
https://ncbi.nlm.nih.gov/pubmed/18503712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-44
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