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Synthesis of tenascin and laminin beta2 chain in human bronchial epithelial cells is enhanced by cysteinyl leukotrienes via CysLT(1 )receptor

BACKGROUND: Cysteinyl leukotrienes (CysLTs) are key mediators of asthma, but their role in the genesis of airway remodeling is insufficiently understood. Recent evidence suggests that increased expression of tenascin (Tn) and laminin (Ln) β2 chain is indicative of the remodeling activity in asthma,...

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Detalhes bibliográficos
Main Authors: Altraja, Siiri, Kadai, Martin, Rekker, Erki, Altraja, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2412865/
https://ncbi.nlm.nih.gov/pubmed/18503712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-44
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