Mutant p53 can substitute for human papillomavirus type 16 E6 in immortalization of human keratinocytes but does not have E6-associated trans-activation or transforming activity.

Human papillomavirus type 16 (HPV16) E6 and E7 are selectively retained and expressed in HPV16-associated human genital tumors. E6 is active in several cell culture assays, including transformation of NIH 3T3 cells, trans activation of the adenovirus E2 promoter, and cooperation with E7 to immortali...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Sedman, S A, Hubbert, N L, Vass, W C, Lowy, D R, Schiller, J T
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1318401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.7.4201-4208.1992
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!