A mutation present in the amino terminus of Sabin 3 poliovirus VP1 protein is attenuating.

The attenuated phenotype of Sabin 3 poliovirus compared with its neurovirulent progenitor strain has been largely accounted for by mutations in the genome at positions 472 and 2034 (G. D. Westrop, K. A. Wareham, D. M. A. Evans, G. Dunn, P. D. Minor, D. I. Magrath, F. Taffs, S. Marsden, M. A. Skinner...

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Pubblicato in:	J Virol
Autori principali:	Tatem, J M, Weeks-Levy, C, Georgiu, A, DiMichele, S J, Gorgacz, E J, Racaniello, V R, Cano, F R, Mento, S J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.3194-3197.1992
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