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Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy?
Two-thirds of breast tumours are oestrogen-receptor positive and 60–70% of these tumours respond to interventions that reduce the effects of oestrogen. Until recently, tamoxifen was the drug of choice for the treatment of hormone-responsive early and advanced breast cancer. However, tamoxifen is ass...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2004
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2410276/ https://ncbi.nlm.nih.gov/pubmed/15150604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601731 |
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