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Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy?

Two-thirds of breast tumours are oestrogen-receptor positive and 60–70% of these tumours respond to interventions that reduce the effects of oestrogen. Until recently, tamoxifen was the drug of choice for the treatment of hormone-responsive early and advanced breast cancer. However, tamoxifen is ass...

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Detalhes bibliográficos
Autor principal: Sainsbury, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410276/
https://ncbi.nlm.nih.gov/pubmed/15150604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601731
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