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The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum

The strategy of using estrogen suppression to treat breast cancer led to the development of aromatase inhibitors, including the third-generation nonsteroidal compounds anastrozole and letrozole, and the steroidal compound exemestane. Aromatase inhibitors potently inhibit aromatase activity and also...

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Bibliographic Details
Main Author: Lønning, P. E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042921/
https://ncbi.nlm.nih.gov/pubmed/20616198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdq337
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