Molecular attenuation of vaccinia virus: mutant generation and animal characterization.

These studies demonstrated that the inbred BALB/c mouse strain can be optimized for the assessment of vaccinia virus virulence, growth, and spread from the site of inoculation and immune protection from a lethal vaccinia virus challenge. The studies established that manipulation of the vaccinia viru...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Lee, M S, Roos, J M, McGuigan, L C, Smith, K A, Cormier, N, Cohen, L K, Roberts, B E, Payne, L G
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1560521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.2617-2630.1992
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