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Molecular attenuation of vaccinia virus: mutant generation and animal characterization.

These studies demonstrated that the inbred BALB/c mouse strain can be optimized for the assessment of vaccinia virus virulence, growth, and spread from the site of inoculation and immune protection from a lethal vaccinia virus challenge. The studies established that manipulation of the vaccinia viru...

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Detalhes bibliográficos
Main Authors: Lee, M S, Roos, J M, McGuigan, L C, Smith, K A, Cormier, N, Cohen, L K, Roberts, B E, Payne, L G
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC241015/
https://ncbi.nlm.nih.gov/pubmed/1560521
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