Attenuated vaccinia virus-circumsporozoite protein recombinants confer protection against rodent malaria.

NYVAC-based vaccinia virus recombinants expressing the circumsporozoite protein (CSP) were evaluated in the Plasmodium berghei rodent malaria model system. Immunization of mice with a NYVAC-based CSP recombinant elicited a high level of protection (60 to 100%). Protection did not correlate with CS r...

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Detalhes bibliográficos
Main Authors: Lanar, D E, Tine, J A, de Taisne, C, Seguin, M C, Cox, W I, Winslow, J P, Ware, L A, Kauffman, E B, Gordon, D, Ballou, W R, Paoletti, E, Sadoff, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC173977/
https://ncbi.nlm.nih.gov/pubmed/8613376
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