Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation

Testicular germ cell tumours (TGCT) represent the most common malignancies in young males. Whereas in 1970s, the survival rate in patients with metastatic testicular tumours was only 5%, these days, 80% of the patients treated by modern chemotherapy will survive their disease. The drug that revoluti...

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Autori principali: Schweyer, S, Soruri, A, Meschter, O, Heintze, A, Zschunke, F, Miosge, N, Thelen, P, Schlott, T, Radzun, H J, Fayyazi, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409982/
https://ncbi.nlm.nih.gov/pubmed/15266324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601919
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