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Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells

Testicular germ cell tumour (TGCT) is the most common malignancy in young males. Although most TGCTs are sensitive to cisplatin-based chemotherapy, significant numbers of TGCT patients still relapse and die each year because of the development of resistance to cisplatin. Previously, we first reporte...

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Hlavní autoři: Fung, M K L, Cheung, H-W, Ling, M-T, Cheung, A L M, Wong, Y-C, Wang, X
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360662/
https://ncbi.nlm.nih.gov/pubmed/16880791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603284
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