Association between ERCC1 and XPA expression and polymorphisms and the response to cisplatin in testicular germ cell tumours

BACKGROUND: Cisplatin cures over 80% of testicular germ cell tumours (TGCTs), and nucleotide-excision repair (NER) modifies the sensitivity to cisplatin. We explored the association between NER proteins and their polymorphisms with cisplatin sensitivity (CPS) and overall survival (OS) of patients wi...

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Détails bibliographiques
Auteurs principaux: Mendoza, J, Martínez, J, Hernández, C, Pérez-Montiel, D, Castro, C, Fabián-Morales, E, Santibáñez, M, González-Barrios, R, Díaz-Chávez, J, Andonegui, M A, Reynoso, N, Oñate, L F, Jiménez, M A, Núñez, M, Dyer, R, Herrera, L A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Translational Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708571/
https://ncbi.nlm.nih.gov/pubmed/23807173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.303
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