Capecitabine in combination with mitomycin C in patients with gastrointestinal cancer: results of an extended multicentre phase-I trial

The aim of this study was to determine the dose-limiting toxicity (DLT) and establish the recommended dose for mitomycin C added every 3 weeks to the standard combination dose of capecitabine. Cohorts of at least three patients with pretreated gastrointestinal carcinoma received capecitabine 1000 mg...

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Main Authors: Hofheinz, R-D, Hartmann, J T, Willer, A, Oechsle, K, Hartung, G, Gnad, U, Saussele, S, Kreil, S, Bokemeyer, C, Hehlmann, R, Hochhaus, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Clinical
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409860/
https://ncbi.nlm.nih.gov/pubmed/15238990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602025
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