Capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated tumours: results of an extended phase-I trial

Preclinical data suggest that the anti-tumour activity of capecitabine is enhanced by taxanes and mitomycin C through up-regulation of thymidine phosphorylase (TP). Here, we studied safety and efficacy of the combination of capecitabine with docetaxel and mitomycin C. Two dose levels (DL) were inves...

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Dettagli Bibliografici
Autori principali: Ernst, T, Merx, K, Gnad-Vogt, U, Lukan, N, Kripp, M, Schultheis, B, Hochhaus, A, Hofheinz, R-D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360249/
https://ncbi.nlm.nih.gov/pubmed/18000507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604067
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