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A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer

In this marker evaluation study, we tested whether distinct patterns of functional genomic polymorphisms in genes involved in drug metabolic pathways and DNA repair that predict clinical outcome to 5-fluorouracil (5-FU)/oxaliplatin chemotherapy in patients with advanced colorectal cancer could be id...

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Detalhes bibliográficos
Main Authors: Stoehlmacher, J, Park, D J, Zhang, W, Yang, D, Groshen, S, Zahedy, S, Lenz, H-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409815/
https://ncbi.nlm.nih.gov/pubmed/15213713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601975
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