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Two functionally distinct subsites for the binding of internal blockers to the pore of voltage-activated K(+) channels
Many blockers of Na(+) and K(+) channels act by blocking the pore from the intracellular side. For Shaker K(+) channels, such intracellular blockers vary in their functional effect on slow (C-type) inactivation: Some blockers interfere with C-type inactivation, whereas others do not. These functiona...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24097/ https://ncbi.nlm.nih.gov/pubmed/8917595 |
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