Two functionally distinct subsites for the binding of internal blockers to the pore of voltage-activated K(+) channels
Many blockers of Na(+) and K(+) channels act by blocking the pore from the intracellular side. For Shaker K(+) channels, such intracellular blockers vary in their functional effect on slow (C-type) inactivation: Some blockers interfere with C-type inactivation, whereas others do not. These functiona...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.13357 |
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