Fusion of HIV-1 Tat protein transduction domain to poly-lysine as a new DNA delivery tool

Effective gene therapy depends on the efficient transfer of therapeutic genes to target cells. None of the current technologies, however, satisfy all of the requirements necessary for gene therapy, because the plasma and nuclear membranes of mammalian cells are tight barriers against gene transfer u...

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Dades bibliogràfiques
Autors principals: Hashida, H, Miyamoto, M, Cho, Y, Hida, Y, Kato, K, Kurokawa, T, Okushiba, S, Kondo, S, Dosaka-Akita, H, Katoh, H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409656/
https://ncbi.nlm.nih.gov/pubmed/15026809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601680
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