Fusion of HIV-1 Tat protein transduction domain to poly-lysine as a new DNA delivery tool

Effective gene therapy depends on the efficient transfer of therapeutic genes to target cells. None of the current technologies, however, satisfy all of the requirements necessary for gene therapy, because the plasma and nuclear membranes of mammalian cells are tight barriers against gene transfer u...

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Detalles Bibliográficos
Main Authors: Hashida, H, Miyamoto, M, Cho, Y, Hida, Y, Kato, K, Kurokawa, T, Okushiba, S, Kondo, S, Dosaka-Akita, H, Katoh, H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2004
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409656/
https://ncbi.nlm.nih.gov/pubmed/15026809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601680
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