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Normal expression of DNA repair proteins, hMre11, Rad50 and Rad51 but protracted formation of Rad50 containing foci in X-irradiated skin fibroblasts from radiosensitive cancer patients

About 5% of oncology patients treated by radiation therapy develop acute or late radiotoxic effects whose molecular mechanisms remain poorly understood. In this study, we evaluated the potential role of DNA repair proteins in the hypersensitivity of cancer patients to radiation therapy. The expressi...

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Autors principals: Djuzenova, C, Mühl, B, Schakowski, R, Oppitz, U, Flentje, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409526/
https://ncbi.nlm.nih.gov/pubmed/15150571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601878
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