A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers

Variation in the penetrance estimates for BRCA1 and BRCA2 mutation carriers suggests that other genetic polymorphisms may modify the cancer risk in carriers. The RAD51 gene, which participates in homologous recombination double-strand breaks (DSB) repair in the same pathway as the BRCA1 and BRCA2 ge...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Kadouri, L, Kote-Jarai, Z, Hubert, A, Durocher, F, Abeliovich, D, Glaser, B, Hamburger, T, Eeles, R A, Peretz, T
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2004
Предметы:
Genetics and Genomics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409456/
https://ncbi.nlm.nih.gov/pubmed/15138485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601837
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы