Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: Implications for vaccine design

Immunization with the highly polymorphic Plasmodium falciparum apical membrane antigen 1 (PfAMA1) induces protection in animals but primarily against parasites that express the same or similar alleles. One strategy to overcome the obstacle of polymorphism is to combine PfAMA1 proteins representing m...

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Bibliographische Detailangaben
Hauptverfasser: Duan, Junhui, Mu, Jianbing, Thera, Mahamadou Ali, Joy, Deirdre, Kosakovsky Pond, Sergei L., Diemert, David, Long, Carole, Zhou, Hong, Miura, Kazutoyo, Ouattara, Amed, Dolo, Amagana, Doumbo, Ogobara, Su, Xin-zhuan, Miller, Louis
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409418/
https://ncbi.nlm.nih.gov/pubmed/18515425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802328105
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