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Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system

Complexins (Cplxs) are key regulators of synaptic exocytosis, but whether they act as facilitators or inhibitors is currently being disputed controversially. We show that genetic deletion of all Cplxs expressed in the mouse brain causes a reduction in Ca(2+)-triggered and spontaneous neurotransmitte...

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書誌詳細
主要な著者: Xue, Mingshan, Stradomska, Alicja, Chen, Hongmei, Brose, Nils, Zhang, Weiqi, Rosenmund, Christian, Reim, Kerstin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409395/
https://ncbi.nlm.nih.gov/pubmed/18505837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803012105
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