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Mutation of an A-kinase-anchoring protein causes long-QT syndrome

A-kinase anchoring proteins (AKAPs) recruit signaling molecules and present them to downstream targets to achieve efficient spatial and temporal control of their phosphorylation state. In the heart, sympathetic nervous system (SNS) regulation of cardiac action potential duration (APD), mediated by β...

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Detalhes bibliográficos
Main Authors: Chen, Lei, Marquardt, Michelle L., Tester, David J., Sampson, Kevin J., Ackerman, Michael J., Kass, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409254/
https://ncbi.nlm.nih.gov/pubmed/18093912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710527105
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