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PERTURBATION OF SODIUM CHANNEL STRUCTURE BY AN INHERITED LONG QT SYNDROME MUTATION
The cardiac voltage-gated sodium channel (Na(V)1.5) underlies impulse conduction in the heart and its depolarization-induced inactivation is essential in control of the duration of the QT interval of the electrocardiogram (ECG). Perturbation of Nav1.5 inactivation by drugs or inherited mutation can...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518026/ https://ncbi.nlm.nih.gov/pubmed/22426227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1717 |
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