Retinoblastoma protein and simian virus 40-dependent immortalization of human fibroblasts.
Transformation and immortalization of human diploid fibroblasts by simian virus 40 (SV40) is at least a two-stage process, since transformants have a limited lifespan in culture. We have isolated immortalized derivatives (AR5 and HAL) from transformants generated with an origin-defective SV40 genome...
שמור ב:
| הוצא לאור ב: | J Virol |
|---|---|
| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1991
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1851857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.6.2845-2852.1991 |
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