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OpdA, a bacterial organophosphorus hydrolase, prevents lethality in rats after poisoning with highly toxic organophosphorus pesticides

Organophosphorus (OP) pesticides poison more than 3,000,000 people every year in the developing world, mostly through intentional self-poisoning. Advances in medical therapy for OP poisoning have lagged, and current treatment is not highly effective with mortality of up to 40% in even the most advan...

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Main Authors: Bird, Steven B., Sutherland, Tara D., Gresham, Chip, Oakeshott, John, Scott, Colin, Eddleston, Michael
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408951/
https://ncbi.nlm.nih.gov/pubmed/18378376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2008.02.005
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