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Traf1 Induction and Protection from Tumor Necrosis Factor by Nuclear Factor-κB p65 Is Independent of Serine 536 Phosphorylation

Abnormal nuclear factor-κB (NF-κB) signaling has been attributed to the initiation and progression of cancer. Posttranslational modification of p65 facilitates optimal NF-κB signaling after activation. Here, we show that the phosphorylation of serine 536 was required for p65-mediated transcription a...

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Detalhes bibliográficos
Main Authors: Sasaki, Carl Y., Slemenda, Colin F., Ghosh, Paritosh, Barberi, Theresa J., Longo, Dan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408918/
https://ncbi.nlm.nih.gov/pubmed/18056447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0922
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