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Hypoxia in Human Trophoblasts Stimulates the Expression and Secretion of Connective Tissue Growth Factor

The mechanisms underlying cellular injury when human placental trophoblasts are exposed to hypoxia are unclear. Connective tissue growth factor (CTGF) mediates cell injury and fibrosis in diverse tissues. We hypothesized that hypoxia enhances the production of CTGF in primary term human trophoblasts...

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Autori principali: Rimon, Eli, Chen, Baosheng, Shanks, Anthony L., Nelson, D. Michael, Sadovsky, Yoel
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408813/
https://ncbi.nlm.nih.gov/pubmed/18292194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1099
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