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Hypoxia in Human Trophoblasts Stimulates the Expression and Secretion of Connective Tissue Growth Factor

The mechanisms underlying cellular injury when human placental trophoblasts are exposed to hypoxia are unclear. Connective tissue growth factor (CTGF) mediates cell injury and fibrosis in diverse tissues. We hypothesized that hypoxia enhances the production of CTGF in primary term human trophoblasts...

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Hlavní autoři: Rimon, Eli, Chen, Baosheng, Shanks, Anthony L., Nelson, D. Michael, Sadovsky, Yoel
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408813/
https://ncbi.nlm.nih.gov/pubmed/18292194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1099
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